Integrated Computational Approaches and Tools for Allosteric Drug Discovery

Computational and Structural Approaches in Drug Discovery

Integrated Computational and Experimental Approaches for Accelerated Drug Combination Discovery and Development : Applications in Cancer Pharmacology

Kashif, M. 2015. Integrated Computational and Experimental Approaches for Accelerated Drug Combination Discovery and Development. Applications in Cancer Pharmacology. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1073. 58 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-9177-2. Today the norm in modern cancer treatment is to use different form...

Proteomics: approaches and image analysis tools for drug discovery

Proteomics, the science of proteins is the global study of the expression, interaction and modification of proteins within the body. Since proteins are the intermediaries between genetic instruction and all forms of cell activity, advances in proteomics promise to provide insight into disease and to accelerate systematized discovery of new drugs. Proteomics offers medical reaseach groups a way ...

Computational neuropharmacology: dynamical approaches in drug discovery.

Computational approaches that adopt dynamical models are widely accepted in basic and clinical neuroscience research as indispensable tools with which to understand normal and pathological neuronal mechanisms. Although computer-aided techniques have been used in pharmaceutical research (e.g. in structure- and ligand-based drug design), the power of dynamical models has not yet been exploited in...

Computational Approaches for Drug Design and Discovery: An Overview

The process of drug discovery is very complex and requires an interdisciplinary effort to design effective and commercially feasible drugs. The objective of drug design is to find a chemical compound that can fit to a specific cavity on a protein target both geometrically and chemically. After passing the animal tests and human clinical trials, this compound becomes a drug available to patients...